Risk factors for liver diseases are heavy alcohol consumption, chronic infectious hepatitis, fatty liver (hepatic steatosis), male sex, impaired immune system (HIV, immunosuppressive drugs), insulin resistance (ß-cell dysfunction, increased intact proinsulin), age over 50 years.
The IVD biomarker correlates linearly with liver development from healthy organ (F0, ≤54 ng/ml) via fatty liver (F1, 54-79 ng/ml) and liver fibrosis (F2, F3, 80-134 ng/ml) to irreversible liver cirrhosis (≥135 ng/ml).
The test shows a qualitative result starting at level F2 and above. The quantitative values can be determined immediately in the field using a scanning device.